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MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers.
Alhalabi, Omar; Chen, Jianfeng; Zhang, Yuxue; Lu, Yang; Wang, Qi; Ramachandran, Sumankalai; Tidwell, Rebecca Slack; Han, Guangchun; Yan, Xinmiao; Meng, Jieru; Wang, Ruiping; Hoang, Anh G; Wang, Wei-Lien; Song, Jian; Lopez, Lidia; Andreev-Drakhlin, Alex; Siefker-Radtke, Arlene; Zhang, Xinqiao; Benedict, William F; Shah, Amishi Y; Wang, Jennifer; Msaouel, Pavlos; Zhang, Miao; Guo, Charles C; Czerniak, Bogdan; Behrens, Carmen; Soto, Luisa; Papadimitrakopoulou, Vassiliki; Lewis, Jeff; Rinsurongkawong, Waree; Rinsurongkawong, Vadeerat; Lee, Jack; Roth, Jack; Swisher, Stephen; Wistuba, Ignacio; Heymach, John; Wang, Jing; Campbell, Matthew T; Efstathiou, Eleni; Titus, Mark; Logothetis, Christopher J; Ho, Thai H; Zhang, Jianjun; Wang, Linghua; Gao, Jianjun.
Afiliación
  • Alhalabi O; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chen J; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Zhang Y; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lu Y; Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang Q; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Ramachandran S; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Tidwell RS; Department of Biostatistics,, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Han G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Yan X; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Meng J; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Hoang AG; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang WL; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Song J; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lopez L; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Andreev-Drakhlin A; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Siefker-Radtke A; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Zhang X; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Benedict WF; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Shah AY; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang J; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Msaouel P; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Zhang M; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Guo CC; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Czerniak B; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Behrens C; Department of Thoracic, Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Soto L; Department of Translational molecular pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Papadimitrakopoulou V; Department of Thoracic, Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lewis J; Department of Biostatistics,, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Rinsurongkawong W; Department of Biostatistics,, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Rinsurongkawong V; Department of Biostatistics,, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lee J; Department of Biostatistics,, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Roth J; Department of Thoracic and Cardiovascular surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Swisher S; Department of Thoracic and Cardiovascular surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wistuba I; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Heymach J; Department of Thoracic, Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Campbell MT; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Efstathiou E; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Titus M; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Logothetis CJ; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Ho TH; Division of Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
  • Zhang J; Department of Thoracic, Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. LWang22@mdanderson.org.
  • Gao J; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences (GSBS), Houston, TX, USA. LWang22@mdanderson.org.
Nat Commun ; 13(1): 1797, 2022 04 04.
Article en En | MEDLINE | ID: mdl-35379845

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria / Carcinoma de Células Transicionales / Antagonistas del Ácido Fólico Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria / Carcinoma de Células Transicionales / Antagonistas del Ácido Fólico Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos