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Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study.
Piccini, Jonathan P; Caso, Valeria; Connolly, Stuart J; Fox, Keith A A; Oldgren, Jonas; Jones, W Schuyler; Gorog, Diana A; Durdil, Václav; Viethen, Thomas; Neumann, Christoph; Mundl, Hardi; Patel, Manesh R.
Afiliación
  • Piccini JP; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA. Electronic address: jonathan.piccini@duke.edu.
  • Caso V; University of Perugia Stroke Unit, Perugia, Italy.
  • Connolly SJ; Population Health Research Institute, McMaster University, Hamilton, ON, Canada; Hamilton Health Services, Hamilton, ON, Canada.
  • Fox KAA; Division of Medical and Radiological Sciences, University of Edinburgh, Edinburgh, UK.
  • Oldgren J; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
  • Jones WS; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA.
  • Gorog DA; National Heart and Lung Institute, Imperial College London, London, UK; University of Hertfordshire, Hatfield, UK.
  • Durdil V; University Hospital Motol, Prague, Czech Republic.
  • Viethen T; Bayer, Wuppertal, Germany.
  • Neumann C; Bayer, Wuppertal, Germany.
  • Mundl H; Bayer, Wuppertal, Germany.
  • Patel MR; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA.
Lancet ; 399(10333): 1383-1390, 2022 04 09.
Article en En | MEDLINE | ID: mdl-35385695
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrilación Atrial / Inhibidores del Factor Xa / Anticoagulantes Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Lancet Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrilación Atrial / Inhibidores del Factor Xa / Anticoagulantes Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Lancet Año: 2022 Tipo del documento: Article