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Demonstration of a Common DPhe7 to DNal(2')7 Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides.
Gimenez, Luis E; Noblin, Terry A; Williams, Savannah Y; Mullick Bagchi, Satarupa; Ji, Ren-Lei; Tao, Ya-Xiong; Jeppesen, Claus B; Conde-Frieboes, Kilian W; Sawyer, Tomi K; Grieco, Paolo; Cone, Roger D.
Afiliación
  • Gimenez LE; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Noblin TA; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Williams SY; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Mullick Bagchi S; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Ji RL; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, United States.
  • Tao YX; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, United States.
  • Jeppesen CB; Global Drug Discovery, Novo Nordisk A/S, 2760 Måløv, Denmark.
  • Conde-Frieboes KW; Global Research Technology, Novo Nordisk A/S, 2760 Måløv, Denmark.
  • Sawyer TK; Courage Therapeutics, 64 Homer Street, Newton, Massachusetts 02459, United States.
  • Cone RD; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
J Med Chem ; 65(8): 5990-6000, 2022 04 28.
Article en En | MEDLINE | ID: mdl-35404053
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Corticotropina / Melanocortinas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Corticotropina / Melanocortinas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos