Bioinformatic identification of previously unrecognized amyloidogenic proteins.

Rosenberg, Gregory M; Murray, Kevin A; Salwinski, Lukasz; Hughes, Michael P; Abskharon, Romany; Eisenberg, David S

Rosenberg, Gregory M; Murray, Kevin A; Salwinski, Lukasz; Hughes, Michael P; Abskharon, Romany; Eisenberg, David S.

Afiliación

Rosenberg GM; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA.
Murray KA; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA.
Salwinski L; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA.
Hughes MP; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA; Department of Cell and Molecular Biology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Abskharon R; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA.
Eisenberg DS; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, Molecular Biology Institute, and Howard Hughes Medical Institute, UCLA, Los Angeles, California, USA. Electronic address: david@mbi.ucla.edu.

J Biol Chem ; 298(5): 101920, 2022 05.

Article en En | MEDLINE | ID: mdl-35405097

Asunto(s)

Proteínas Amiloidogénicas; Amiloidosis; Biología Computacional; Amiloide/genética; Amiloide/metabolismo; Proteínas Amiloidogénicas/genética; Amiloidosis/metabolismo; Amiloidosis/patología; Humanos; Mutación; Proteoma/genética

Palabras clave

CharcotMarieTooth disease electron microscopy; amyloid; intrinsically disordered protein; low-complexity domain; protein structure

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biología Computacional / Proteínas Amiloidogénicas / Amiloidosis Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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