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TLR8 is activated by 5'-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway.
Köllisch, Gabriele; Solis, Francisco Venegas; Obermann, Hannah-Lena; Eckert, Jeannine; Müller, Thomas; Vierbuchen, Tim; Rickmeyer, Thomas; Muche, Simon; Przyborski, Jude M; Heine, Holger; Kaufmann, Andreas; Baumeister, Stefan; Lingelbach, Klaus; Bauer, Stefan.
Afiliación
  • Köllisch G; Department of Parasitology, Philipps University Marburg, 35043 Marburg, Germany.
  • Solis FV; Institute for Immunology, Philipps University Marburg, BMFZ, 35043 Marburg, Germany.
  • Obermann HL; Institute for Immunology, Philipps University Marburg, BMFZ, 35043 Marburg, Germany.
  • Eckert J; Department of Parasitology, Philipps University Marburg, 35043 Marburg, Germany.
  • Müller T; Institute for Medical Microbiology, Immunology und Hygiene, Technical University Munich, Munich, Germany.
  • Vierbuchen T; Division of Innate Immunity, Research Center Borstel, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Borstel, Germany.
  • Rickmeyer T; Institute for Pharmaceutical Chemistry, Philipps University Marburg, 35043 Marburg, Germany.
  • Muche S; Department of Chemistry, Philipps University Marburg, 35043 Marburg, Germany.
  • Przyborski JM; Department of Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University Giessen, Giessen, Germany.
  • Heine H; Division of Innate Immunity, Research Center Borstel, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Borstel, Germany.
  • Kaufmann A; Institute for Immunology, Philipps University Marburg, BMFZ, 35043 Marburg, Germany.
  • Baumeister S; Department of Parasitology, Philipps University Marburg, 35043 Marburg, Germany.
  • Lingelbach K; Department of Parasitology, Philipps University Marburg, 35043 Marburg, Germany.
  • Bauer S; Institute for Immunology, Philipps University Marburg, BMFZ, 35043 Marburg, Germany. Electronic address: stefan.bauer@staff.uni-marburg.de.
Cell Rep ; 39(2): 110691, 2022 04 12.
Article en En | MEDLINE | ID: mdl-35417716

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Malaria Falciparum / Receptor Toll-Like 8 / Metiltioinosina Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Malaria Falciparum / Receptor Toll-Like 8 / Metiltioinosina Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Alemania