Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-&#954;B signaling pathway.

Han, Xue; Zhang, Jiajia; Zhou, Li; Wei, Jiajia; Tu, Yu; Shi, Qiaojuan; Zhang, Yi; Ren, Juan; Wang, Yi; Ying, Huazhong; Liang, Guang

Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.

Han, Xue; Zhang, Jiajia; Zhou, Li; Wei, Jiajia; Tu, Yu; Shi, Qiaojuan; Zhang, Yi; Ren, Juan; Wang, Yi; Ying, Huazhong; Liang, Guang.

Afiliación

Han X; Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research, Hangzhou Medical College, Hangzhou, China.
Zhang J; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Zhou L; Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research, Hangzhou Medical College, Hangzhou, China.
Wei J; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Tu Y; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Shi Q; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Zhang Y; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Ren J; Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research, Hangzhou Medical College, Hangzhou, China.
Wang Y; Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research, Hangzhou Medical College, Hangzhou, China.
Ying H; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Liang G; Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research, Hangzhou Medical College, Hangzhou, China.

Phytother Res ; 36(6): 2511-2523, 2022 Jun.

Article en En | MEDLINE | ID: mdl-35434887

Asunto(s)

Diabetes Mellitus Experimental; Nefropatías Diabéticas; Diterpenos; Hiperglucemia; Animales; Citocinas/metabolismo; Diabetes Mellitus Experimental/complicaciones; Diabetes Mellitus Experimental/tratamiento farmacológico; Diabetes Mellitus Experimental/metabolismo; Nefropatías Diabéticas/tratamiento farmacológico; Diterpenos/farmacología; Fibrosis; Glucosa/metabolismo; Hiperglucemia/complicaciones; Hiperglucemia/tratamiento farmacológico; Hiperglucemia/metabolismo; Inflamación/tratamiento farmacológico; Riñón; Ratones; Proteínas Quinasas Activadas por Mitógenos/metabolismo; FN-kappa B/metabolismo; Transducción de Señal

Palabras clave

diabetic nephropathy; inflammation; mitogen-activated protein kinase; nuclear factor kappa B; sclareol

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Nefropatías Diabéticas / Diterpenos / Hiperglucemia Límite: Animals Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2022 Tipo del documento: Article País de afiliación: China

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