5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study.

Pflégr, Václav; Stepánková, Sárka; Svrcková, Katarína; Svarcová, Markéta; Vinsová, Jarmila; Krátký, Martin

Pflégr, Václav; Stepánková, Sárka; Svrcková, Katarína; Svarcová, Markéta; Vinsová, Jarmila; Krátký, Martin.

Afiliación

Pflégr V; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Stepánková S; Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
Svrcková K; Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
Svarcová M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Vinsová J; Department of Chemistry, Faculty of Science, J. E. Purkinje University, Pasteurova 3632/15, 400 96 Ústí nad Labem, Czech Republic.
Krátký M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

Pharmaceuticals (Basel) ; 15(4)2022 Mar 25.

Article en En | MEDLINE | ID: mdl-35455397

Palabras clave

1,3,4-oxadiazole; 1,3,4-thiadiazole; acetylcholinesterase; butyrylcholinesterase; enzyme inhibition; molecular docking

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2022 Tipo del documento: Article País de afiliación: República Checa

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