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Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA).
Rosas, Ivan O; Bräu, Norbert; Waters, Michael; Go, Ronaldo C; Malhotra, Atul; Hunter, Bradley D; Bhagani, Sanjay; Skiest, Daniel; Savic, Sinisa; Douglas, Ivor S; Garcia-Diaz, Julia; Aziz, Mariam S; Cooper, Nichola; Youngstein, Taryn; Sorbo, Lorenzo Del; Zerda, David J De La; Ustianowski, Andrew; Gracian, Antonio Cubillo; Blyth, Kevin G; Carratalà, Jordi; François, Bruno; Benfield, Thomas; Haslem, Derrick; Bonfanti, Paolo; van der Leest, Cor H; Rohatgi, Nidhi; Wiese, Lothar; Luyt, Charles Edouard; Bauer, Rebecca N; Cai, Fang; Lee, Ivan T; Matharu, Balpreet; Metcalf, Louis; Wildum, Steffen; Graham, Emily; Tsai, Larry; Bao, Min.
Afiliación
  • Rosas IO; Pulmonary, Critical Care, and Sleep Medicine, Baylor College of Medicine, 7200 Cambridge Street, Houston, TX 77030, USA.
  • Bräu N; James J. Peters Veterans Affairs Medical Center, Bronx, and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Waters M; eStudy Site, Chula Vista, CA, USA.
  • Go RC; Hackensack Meridian School of Medicine and Hackensack University Medical Center, Hackensack, NJ, USA.
  • Malhotra A; University of California San Diego, La Jolla, CA, USA.
  • Hunter BD; Intermountain Healthcare, Salt Lake City, UT, USA.
  • Bhagani S; Royal Free Hospital, London, UK.
  • Skiest D; University of Massachusetts Medical School-Baystate, Springfield, MA, USA.
  • Savic S; Leeds Teaching Hospitals NHS Trust and National Institute for Health Research-Leeds, Biomedical Research Centre, Leeds, UK.
  • Douglas IS; Denver Health Medical Center, Denver, and University of Colorado, Anschutz School of Medicine, Aurora, CO, USA.
  • Garcia-Diaz J; Ochsner Clinic Foundation, New Orleans, LA, USA.
  • Aziz MS; Rush University Medical Center, Chicago, IL, USA.
  • Cooper N; Imperial College London, London, UK.
  • Youngstein T; Imperial College London, London, UK.
  • Sorbo LD; University Health Network, Toronto, ON, Canada.
  • Zerda DJ; University of Miami Miller School of Medicine, Miami, FL, USA.
  • Ustianowski A; North Manchester General Hospital, Manchester, UK.
  • Gracian AC; Hospital Universitario HM Sanchinarro, Centro Integral, Oncológico Clara Campal, and Departamento de Ciencias Médicas Clínicas, Facultad de Medicina, Universidad CEU San Pablo, Madrid, Spain.
  • Blyth KG; Institute of Cancer Sciences, University of Glasgow/Department of Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
  • Carratalà J; Department of Infectious Diseases, Bellvitge University Hospital, Bellvitge Biomedical Research Institute, University of Barcelona, and CIBERINFEC, Barcelona, Spain.
  • François B; Intensive Care Unit and Inserm CIC1435 and UMR1092, CHU Limoges, Limoges, France.
  • Benfield T; Center of Research and Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital-Amager and Hvidovre, Hvidovre, Denmark.
  • Haslem D; Intermountain Medical Group, St George, UT, USA.
  • Bonfanti P; University of Milano-Bicocca and Azienda Ospedaliera San Gerardo di Monza, Monza, Italy.
  • van der Leest CH; Amphia Ziekenhuis, Breda, the Netherlands.
  • Rohatgi N; Division of Hospital Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Wiese L; Department of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark.
  • Luyt CE; Hôpital de la Pitié Salpêtrière, Paris, France.
  • Bauer RN; Genentech, South San Francisco, CA, USA.
  • Cai F; Genentech, South San Francisco, CA, USA.
  • Lee IT; Genentech, South San Francisco, CA, USA.
  • Matharu B; Roche Products Ltd, Welwyn Garden City, UK.
  • Metcalf L; Roche Products Ltd, Welwyn Garden City, UK.
  • Wildum S; F Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Graham E; Roche Products Ltd, Welwyn Garden City, UK.
  • Tsai L; Genentech, South San Francisco, CA, USA.
  • Bao M; Genentech, South San Francisco, CA, USA.
EClinicalMedicine ; 47: 101409, 2022 May.
Article en En | MEDLINE | ID: mdl-35475258

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: EClinicalMedicine Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: EClinicalMedicine Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos