Your browser doesn't support javascript.
loading
A Cross-Sectional Study of Ocular Changes in Children and Adolescents with Diabetes Mellitus in Selected Health Facilities in Ghana.
Essuman, Vera A; Tagoe, Naa N; Essuman, Akye; Abaidoo, Benjamin; Akpalu, Josephine; Sackey, Harold A; Hayfron-Benjamin, Charles F; Asare, George; Amoah, Albert G B; Ndanu, Thomas A; Ofori-Adjei, Imelda D B; Barnes, Nana A; Appiah-Thompson, Benedicta L; Amoaku, Winfried M.
Afiliación
  • Essuman VA; Ophthalmology Unit, Department of Surgery, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Tagoe NN; Eye Department, Korle Bu Teaching Hospital, Accra P.O. Box 77, Ghana.
  • Essuman A; Eye Department, Korle Bu Teaching Hospital, Accra P.O. Box 77, Ghana.
  • Abaidoo B; Department of Community Health, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Akpalu J; Ophthalmology Unit, Department of Surgery, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Sackey HA; Department of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Hayfron-Benjamin CF; Department of Child Health, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Asare G; Department of Physiology, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Amoah AGB; Department of Anaesthesia, Korle Bu Teaching Hospital, Korle Bu, Accra P.O. Box GP 4236, Ghana.
  • Ndanu TA; Chemical Pathology Unit, Department of Medical Laboratory Sciences, University of Ghana School of Basic and Allied Health Sciences, College of Health Sciences, Accra P.O. Box GP 4236, Ghana.
  • Ofori-Adjei IDB; Department of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Barnes NA; National Diabetes Management and Research Centre (NDMRC), Korle Bu Teaching Hospital, Accra P.O. Box GP 4236, Ghana.
  • Appiah-Thompson BL; Department of Preventive & Community Dentistry, University of Ghana Dental School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
  • Amoaku WM; Eye Department, Korle Bu Teaching Hospital, Accra P.O. Box 77, Ghana.
Int J Environ Res Public Health ; 19(9)2022 04 27.
Article en En | MEDLINE | ID: mdl-35564690
ABSTRACT

BACKGROUND:

The main objective of the study was to determine the prevalence of diabetic retinopathy (DR), other diabetes-related ocular changes (e.g., cataracts, corneal ulceration), and non-diabetic ocular disease in Ghanaian children and adolescents. The second objective was to evaluate the relationship between these conditions and age at diagnosis, current age, diabetes mellitus (DM) duration, and participant's sex.

METHODS:

A cross-sectional study, undertaken by a multidisciplinary team, included a cohort of children and adolescents (4-19 years) with DM recruited from selected health facilities in Ghana, from March 2016 to September 2019, after written informed consent or assent. The cohort will be followed up for 3 years to determine the natural course of the ocular changes, reported later. Participants were examined for all microvascular and macrovascular complications, non-diabetic ocular disease, anthropometric measurements, laboratory characteristics and quality of life issues. Full ocular examination was also undertaken. Statistical Package for Social Sciences (SPSS Version 25.0) was used for the data analysis. Continuous and categorical variables were presented as mean and standard deviation (SD), median (interquartile range) and as percentages (%), respectively. T-test and Mann-Whitney U test were used in establishing associations.

RESULTS:

A total of 58 participants were recruited. DR was detected in only 1 out of 58 (1.7%) participants at baseline. Cataracts were the most common ocular finding, detected in 42 (72%) at baseline. Other anterior segment changes observed included blepharitis 46 (79.3%) and tear film instability 38 (65.5%). There was a significant positive association between duration of the DM and the risk of cataract (p = 0.027). Participants' age at diagnosis was significantly associated with the presence of prominent corneal nerves (p = 0.004).

CONCLUSIONS:

DR was uncommon in this cohort of young persons with DM in Ghana. Cataracts, blepharitis and refractive errors were ocular changes commonly observed. All young persons with diabetes should undergo regular eye examination in all clinics where follow-up care is provided.
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Blefaritis / Catarata / Diabetes Mellitus Tipo 2 / Retinopatía Diabética Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Child / Humans País/Región como asunto: Africa Idioma: En Revista: Int J Environ Res Public Health Año: 2022 Tipo del documento: Article País de afiliación: Ghana
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Blefaritis / Catarata / Diabetes Mellitus Tipo 2 / Retinopatía Diabética Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Child / Humans País/Región como asunto: Africa Idioma: En Revista: Int J Environ Res Public Health Año: 2022 Tipo del documento: Article País de afiliación: Ghana