Predictors of Postacute Sequelae of COVID-19 Development and Rehabilitation: A Retrospective Study.
Arch Phys Med Rehabil
; 103(10): 2001-2008, 2022 10.
Article
en En
| MEDLINE
| ID: mdl-35569640
ABSTRACT
OBJECTIVE:
To examine the frequency of postacute sequelae of SARS-CoV-2 (PASC) and the factors associated with rehabilitation utilization in a large adult population with PASC.DESIGN:
Retrospective study.SETTING:
Midwest hospital health system.PARTICIPANTS:
19,792 patients with COVID-19 from March 10, 2020, to January 17, 2021. INTERVENTION Not applicable. MAIN OUTCOMEMEASURES:
Descriptive analyses were conducted across the entire cohort along with an adult subgroup analysis. A logistic regression was performed to assess factors associated with PASC development and rehabilitation utilization.RESULTS:
In an analysis of 19,792 patients, the frequency of PASC was 42.8% in the adult population. Patients with PASC compared with those without had a higher utilization of rehabilitation services (8.6% vs 3.8%, P<.001). Risk factors for rehabilitation utilization in patients with PASC included younger age (odds ratio [OR], 0.99; 95% confidence interval [CI], 0.98-1.00; P=.01). In addition to several comorbidities and demographics factors, risk factors for rehabilitation utilization solely in the inpatient population included male sex (OR, 1.24; 95% CI, 1.02-1.50; P=.03) with patients on angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers 3 months prior to COVID-19 infections having a decreased risk of needing rehabilitation (OR, 0.80; 95% CI, 0.64-0.99; P=.04).CONCLUSIONS:
Patients with PASC had higher rehabilitation utilization. We identified several clinical and demographic factors associated with the development of PASC and rehabilitation utilization.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
COVID-19
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Arch Phys Med Rehabil
Año:
2022
Tipo del documento:
Article