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The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Guthertz, N; van der Kant, R; Martinez, R M; Xu, Y; Trinh, C H; Iorga, B I; Rousseau, F; Schymkowitz, J; Brockwell, D J; Radford, S E.
Afiliación
  • Guthertz N; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • van der Kant R; Switch Laboratory, VIB-KU Leuven Center for Brain & Disease Research, 3000 Leuven, Belgium.
  • Martinez RM; Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.
  • Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Trinh CH; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Iorga BI; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Rousseau F; Université Paris-Saclay, CNRS UPR 2301, Institut de Chimie des Substances Naturelles, 91198 Gif-sur-Yvette, France.
  • Schymkowitz J; Switch Laboratory, VIB-KU Leuven Center for Brain & Disease Research, 3000 Leuven, Belgium.
  • Brockwell DJ; Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.
  • Radford SE; Switch Laboratory, VIB-KU Leuven Center for Brain & Disease Research, 3000 Leuven, Belgium.
Proc Natl Acad Sci U S A ; 119(22): e2200468119, 2022 05 31.
Article en En | MEDLINE | ID: mdl-35613051
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microglobulina beta-2 / Agregación Patológica de Proteínas / Amiloidosis Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microglobulina beta-2 / Agregación Patológica de Proteínas / Amiloidosis Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido