Molecular design of a pathogen activated, self-assembling mechanopharmaceutical device.

Willmer, Andrew R; Nie, Jiayi; George De la Rosa, Mery Vet; Wen, Winnie; Dunne, Steven; Rosania, Gus R

Willmer, Andrew R; Nie, Jiayi; George De la Rosa, Mery Vet; Wen, Winnie; Dunne, Steven; Rosania, Gus R.

Afiliación

Willmer AR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: awillmer@umich.edu.
Nie J; Department of Biostatistics, University of Southern California, Los Angeles, CA 90089, USA.
George De la Rosa MV; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.
Wen W; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.
Dunne S; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Rosania GR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.

J Control Release ; 347: 620-631, 2022 07.

Article en En | MEDLINE | ID: mdl-35623493

Asunto(s)

Clofazimina; Macrófagos; Animales; Cuerpos de Inclusión; Macrófagos/fisiología; Ratones; Ratones Endogámicos C57BL; Solubilidad

Palabras clave

Drug targeting; Drug-delivery; Modeling and simulation; Pandemic response; Pharmacokinetics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Clofazimina / Macrófagos Límite: Animals Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article

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