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Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies.
Yadav, Rajbharan; Sukumaran, Siddharth; Zabka, Tanja S; Li, Jinze; Oldendorp, Amy; Morrow, Gary; Reyes, Arthur; Cheu, Melissa; Li, Jessica; Wallin, Jeffrey J; Tsai, Siao; Sun, Laura; Wang, Peiyin; Ellerman, Diego; Spiess, Christoph; Polson, Andy; Stefanich, Eric G; Kamath, Amrita V; Ovacik, Meric A.
Afiliación
  • Yadav R; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Sukumaran S; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Zabka TS; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Li J; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Oldendorp A; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Morrow G; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Reyes A; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Cheu M; BioAnalytical Sciences, Genentech Inc., South San Francisco, CA 94080, USA.
  • Li J; Oncology Biomarker Development (OBD), Genentech Inc., South San Francisco, CA 94080, USA.
  • Wallin JJ; Oncology Biomarker Development (OBD), Genentech Inc., South San Francisco, CA 94080, USA.
  • Tsai S; Biochemical and Cellular Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Sun L; Translational Oncology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Wang P; Translational Oncology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Ellerman D; Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
  • Spiess C; Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
  • Polson A; Translational Oncology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Stefanich EG; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Kamath AV; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Ovacik MA; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Pharmaceutics ; 14(5)2022 Apr 30.
Article en En | MEDLINE | ID: mdl-35631556
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Pharmaceutics Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Pharmaceutics Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos