Kidney transplantation across positive B and T cell crossmatches.
Transplantation
; 26(2): 84-6, 1978 Aug.
Article
en En
| MEDLINE
| ID: mdl-356356
ABSTRACT
Cadaveric renal transplants were performed despite a positive conventional crossmatch (usually intermediate positive) resulting from donor-specific B cell lymphocytotoxins (both IgG and IgM) or IgM cold-reactive T cell lymphocytotoxins. Graft survival at 2 months was 72% in the 14 patients with B cell-specific antibodies and 71% in the 7 recipients with T cell antibodies. No correlation was observed between graft rejection and warm (mainly IgG) or cold (IgM) B cell-specific antibodies. These results indicate that not all positive crossmatches are a contraindication to transplantation. Attempts should be made to study the nature of the lymphocytotoxins before withholding the allograft from the recipient.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Prueba de Histocompatibilidad
/
Trasplante de Riñón
/
Suero Antilinfocítico
Límite:
Humans
Idioma:
En
Revista:
Transplantation
Año:
1978
Tipo del documento:
Article