High-throughput, single-microbe genomics with strain resolution, applied to a human gut microbiome.

Zheng, Wenshan; Zhao, Shijie; Yin, Yehang; Zhang, Huidan; Needham, David M; Evans, Ethan D; Dai, Chengzhen L; Lu, Peter J; Alm, Eric J; Weitz, David A

Zheng, Wenshan; Zhao, Shijie; Yin, Yehang; Zhang, Huidan; Needham, David M; Evans, Ethan D; Dai, Chengzhen L; Lu, Peter J; Alm, Eric J; Weitz, David A.

Afiliación

Zheng W; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
Zhao S; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Yin Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Zhang H; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Needham DM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Evans ED; College of Computer Science and Technology, Zhejiang University, Hangzhou, Zhejiang, China.
Dai CL; School of Engineering and Applied Sciences (SEAS), Harvard University, Cambridge, MA, USA.
Lu PJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Alm EJ; Ocean Ecosystems Biology, GEOMAR, Helmholtz Centre for Ocean Research, Kiel, Germany.
Weitz DA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Science ; 376(6597): eabm1483, 2022 06 03.

Article en En | MEDLINE | ID: mdl-35653470

Asunto(s)

Bacterias; Microbioma Gastrointestinal; Interacciones Microbianas; Bacterias/genética; Bacteriófagos/genética; Bacteroides/genética; Bacteroides/virología; ADN Bacteriano/genética; Microbioma Gastrointestinal/genética; Transferencia de Gen Horizontal; Genoma Bacteriano; Genómica/métodos; Secuenciación de Nucleótidos de Alto Rendimiento; Humanos; Análisis de la Célula Individual/métodos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Interacciones Microbianas / Microbioma Gastrointestinal Límite: Humans Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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