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Downregulation of hERG channel expression by tyrosine kinase inhibitors nilotinib and vandetanib predominantly contributes to arrhythmogenesis.
Cui, Xiaoyan; Sun, Jinglei; Li, Congxin; Qiu, Suhua; Shi, Chenxia; Ma, Jingtao; Xu, Yanfang.
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  • Cui X; Department of Pharmacology, Hebei Medical University; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang 050017, China.
  • Sun J; Department of Pharmacology, Hebei Medical University; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang 050017, China.
  • Li C; Department of Pharmacy, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
  • Qiu S; Department of Pharmacology, Hebei Medical University; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang 050017, China.
  • Shi C; Department of Pharmacology, Hebei Medical University; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang 050017, China.
  • Ma J; Department of Cardiology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050010, China.
  • Xu Y; Department of Pharmacology, Hebei Medical University; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang 050017, China. Electronic address: yanfangxu@hebmu.edu.cn.
Toxicol Lett ; 365: 11-23, 2022 Jul 15.
Article en En | MEDLINE | ID: mdl-35680041
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Canales de Potasio Éter-A-Go-Go / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2022 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Canales de Potasio Éter-A-Go-Go / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2022 Tipo del documento: Article País de afiliación: China