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Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Gordon, Khloe S; Kyung, Taeyoon; Perez, Caleb R; Holec, Patrick V; Ramos, Azucena; Zhang, Angela Q; Agarwal, Yash; Liu, Yunpeng; Koch, Catherine E; Starchenko, Alina; Joughin, Brian A; Lauffenburger, Douglas A; Irvine, Darrell J; Hemann, Michael T; Birnbaum, Michael E.
Afiliación
  • Gordon KS; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Kyung T; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Perez CR; Singapore-MIT Alliance for Research and Technology Centre, Singapore, Singapore.
  • Holec PV; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Ramos A; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Zhang AQ; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Agarwal Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Liu Y; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Koch CE; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Starchenko A; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Joughin BA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lauffenburger DA; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Irvine DJ; Department of Health, Science, and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Hemann MT; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
  • Birnbaum ME; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nat Biomed Eng ; 6(7): 855-866, 2022 07.
Article en En | MEDLINE | ID: mdl-35710755

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Receptores Quiméricos de Antígenos / Neoplasias Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Nat Biomed Eng Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Receptores Quiméricos de Antígenos / Neoplasias Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Nat Biomed Eng Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos