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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms.
Flynn, Julia M; Samant, Neha; Schneider-Nachum, Gily; Barkan, David T; Yilmaz, Nese Kurt; Schiffer, Celia A; Moquin, Stephanie A; Dovala, Dustin; Bolon, Daniel N A.
Afiliación
  • Flynn JM; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
  • Samant N; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
  • Schneider-Nachum G; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
  • Barkan DT; Novartis Institutes for Biomedical Research, Emeryville, United States.
  • Yilmaz NK; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
  • Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
  • Moquin SA; Novartis Institutes for Biomedical Research, Emeryville, United States.
  • Dovala D; Novartis Institutes for Biomedical Research, Emeryville, United States.
  • Bolon DNA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, United States.
Elife ; 112022 06 20.
Article en En | MEDLINE | ID: mdl-35723575

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos