Your browser doesn't support javascript.
loading
Lung Transplant as a Treatment for Patients with End-Stage Respiratory Failure Due to COVID-19.
Urlik, Maciej; Stacel, Tomasz; Latos, Magdalena; Pasek, Piotr; Pióro, Anna; Zawadzki, Fryderyk; Gmerek, Marta; Ksiezopolska, Paulina; Przybylowski, Piotr; Ochman, Marek.
Afiliación
  • Urlik M; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Stacel T; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Latos M; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland. Electronic address: latos.magdalena93@gmail.com.
  • Pasek P; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Pióro A; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Zawadzki F; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Gmerek M; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Ksiezopolska P; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Przybylowski P; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
  • Ochman M; Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia, Katowice, Poland.
Transplant Proc ; 54(4): 908-912, 2022 May.
Article en En | MEDLINE | ID: mdl-35725595
BACKGROUND: COVID-19 may lead to development of irreversible acute respiratory distress syndrome. Some patients sustain severe respiratory failure after infection subsides. They may require lung transplant as a last resort treatment. The aim of the study is to assess the effect and feasibility of lung transplant as a treatment for patients with severe irreversible respiratory failure due to COVID-19. METHODS: This retrospective study pertains to analysis of 119 patients in critical condition who were referred to Lung Transplant Ward (Zabrze, Poland). between July 2020 and June 2021 after developing respiratory failure requiring extracorporeal membrane oxygenation, invasive ventilation, or both, as well as a few patients on high-flow oxygen therapy. Inclusion criteria for referral were confirmed lack of viral disease and exhaustion of other therapeutic options. RESULTS: Of the referred patients, 21.84% were disqualified from such treatment owing to existing contraindications. Among the suitable patients, 75.8% died without transplant. Among all patients who were qualified for lung transplant, only 9 patients became double lung transplant recipients. Intraoperative mortality for this procedure was 33%. Four patients were discharged after the procedure and are currently self-reliant with full respiratory capacity. CONCLUSIONS: Patients with severe irreversible respiratory failure after COVID-19 present significantly high mortality without lung transplant. This procedure may present satisfactory results but must be performed in a timely fashion owing to critical condition and scarcity of lung donors, only aggravated around the time of peak infection waves.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Insuficiencia Respiratoria / Trasplante de Pulmón / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: Transplant Proc Año: 2022 Tipo del documento: Article País de afiliación: Polonia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Insuficiencia Respiratoria / Trasplante de Pulmón / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: Transplant Proc Año: 2022 Tipo del documento: Article País de afiliación: Polonia