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Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.
Shaqra, Ala M; Zvornicanin, Sarah N; Huang, Qiu Yu J; Lockbaum, Gordon J; Knapp, Mark; Tandeske, Laura; Bakan, David T; Flynn, Julia; Bolon, Daniel N A; Moquin, Stephanie; Dovala, Dustin; Kurt Yilmaz, Nese; Schiffer, Celia A.
Afiliación
  • Shaqra AM; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Zvornicanin SN; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Huang QYJ; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Lockbaum GJ; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Knapp M; Novartis Institutes for Biomedical Research, Emeryville, CA, 94608, USA.
  • Tandeske L; Novartis Institutes for Biomedical Research, Emeryville, CA, 94608, USA.
  • Bakan DT; Novartis Institutes for Biomedical Research, Emeryville, CA, 94608, USA.
  • Flynn J; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Bolon DNA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US.
  • Moquin S; Novartis Institutes for Biomedical Research, Emeryville, CA, 94608, USA.
  • Dovala D; Novartis Institutes for Biomedical Research, Emeryville, CA, 94608, USA.
  • Kurt Yilmaz N; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US. Nese.KurtYilmaz@umassmed.edu.
  • Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, US. Celia.Schiffer@umassmed.edu.
Nat Commun ; 13(1): 3556, 2022 06 21.
Article en En | MEDLINE | ID: mdl-35729165
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos