METTL3-mediated m6A modification promotes processing and maturation of <i>pri-miRNA-19a</i> to facilitate nasopharyngeal carcinoma cell proliferation and invasion.

Gong, Yongqian; Jiang, Qingshan; Liu, Lijun; Liao, Qingyun; Yu, Jing; Xiang, Zheng; Luo, Xinggu

METTL3-mediated m6A modification promotes processing and maturation of pri-miRNA-19a to facilitate nasopharyngeal carcinoma cell proliferation and invasion.

Gong, Yongqian; Jiang, Qingshan; Liu, Lijun; Liao, Qingyun; Yu, Jing; Xiang, Zheng; Luo, Xinggu.

Afiliación

Gong Y; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Jiang Q; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Liu L; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Liao Q; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Yu J; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Xiang Z; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Luo X; The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.

Physiol Genomics ; 54(9): 337-349, 2022 09 01.

Article en En | MEDLINE | ID: mdl-35759451

Asunto(s)

MicroARNs; Neoplasias Nasofaríngeas; Animales; Línea Celular Tumoral; Proliferación Celular/genética; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Metiltransferasas/genética; Metiltransferasas/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Carcinoma Nasofaríngeo/genética; Carcinoma Nasofaríngeo/patología; Neoplasias Nasofaríngeas/genética; Neoplasias Nasofaríngeas/patología; Proteínas de Unión al ARN/genética; Proteínas de Unión al ARN/metabolismo

Palabras clave

BAMBI; METTL3; m6A modification; miR-19a-3p; nasopharyngeal carcinoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Nasofaríngeas / MicroARNs Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Physiol Genomics Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: China

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