Structurally-engineered fatty acid 1024 (SEFA-1024) improves diet-induced obesity, insulin resistance, and fatty liver disease.

Secor, Jordon D; Cho, Bennet S; Yu, Lumeng J; Pan, Amy; Ko, Victoria H; Dao, Duy T; Feigh, Michael; Anez-Bustillos, Lorenzo; Fell, Gillian L; Fraser, David A; Gura, Kathleen M; Puder, Mark

Secor, Jordon D; Cho, Bennet S; Yu, Lumeng J; Pan, Amy; Ko, Victoria H; Dao, Duy T; Feigh, Michael; Anez-Bustillos, Lorenzo; Fell, Gillian L; Fraser, David A; Gura, Kathleen M; Puder, Mark.

Afiliación

Secor JD; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Cho BS; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Yu LJ; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Pan A; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Ko VH; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Dao DT; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Feigh M; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Anez-Bustillos L; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Fell GL; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Fraser DA; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Gura KM; Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Puder M; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.

Lipids ; 57(4-5): 241-255, 2022 07.

Article en En | MEDLINE | ID: mdl-35778847

Asunto(s)

Diabetes Mellitus; Resistencia a la Insulina; Enfermedad del Hígado Graso no Alcohólico; Animales; Diabetes Mellitus/metabolismo; Diabetes Mellitus/patología; Dieta Alta en Grasa/efectos adversos; Ácidos Grasos/metabolismo; Péptido 1 Similar al Glucagón/metabolismo; Péptido 1 Similar al Glucagón/farmacología; Péptido 1 Similar al Glucagón/uso terapéutico; Metabolismo de los Lípidos; Hígado/metabolismo; Ratones; Ratones Endogámicos C57BL; Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico; Enfermedad del Hígado Graso no Alcohólico/etiología; Obesidad/genética; Ratas

Palabras clave

fatty acid metabolism; free fatty acid receptors (FFARs); high-fat diet (HFD); hyperglycemia; hyperinsulinemia; lipidomics; lipotoxicity; obesity; structurally-engineered fatty acid (SEFA)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Diabetes Mellitus / Enfermedad del Hígado Graso no Alcohólico Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Lipids Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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