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The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors.
Liu, Lina; Vujovic, Ana; Deshpande, Nandan P; Sathe, Shashank; Anande, Govardhan; Chen, He Tian Tony; Xu, Joshua; Minden, Mark D; Yeo, Gene W; Unnikrishnan, Ashwin; Hope, Kristin J; Lu, Yu.
Afiliación
  • Liu L; Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
  • Vujovic A; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
  • Deshpande NP; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Sathe S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Anande G; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Chen HTT; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Xu J; Adult Cancer Program, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
  • Minden MD; Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.
  • Yeo GW; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California at San Diego, San Diego, CA, USA.
  • Unnikrishnan A; Adult Cancer Program, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
  • Hope KJ; Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.
  • Lu Y; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Nat Commun ; 13(1): 3833, 2022 07 04.
Article en En | MEDLINE | ID: mdl-35781533
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mieloide Aguda / Factores de Empalme de ARN Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mieloide Aguda / Factores de Empalme de ARN Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá