The modification of air particulate matter on the relationship between temperature and childhood asthma hospitalization: An exploration based on different interaction strategies.
Environ Res
; 214(Pt 2): 113848, 2022 11.
Article
en En
| MEDLINE
| ID: mdl-35817164
ABSTRACT
The influence of temperature on childhood asthma was self-evident, yet the issue of whether the relationship will be synergized by air pollution remains unclear. The study aimed to investigate whether the relationship between short-term temperature exposure and childhood asthma hospitalization was modified by particulate matter (PM). Data on childhood asthma hospitalization, meteorological factors, and air pollutants during 2013-2016 in Hefei, China, were collected. First, a basic Poisson regression model combined with a distributed lag nonlinear model was used to assess the temperature-childhood asthma hospitalization relationship. Then, two interactive strategies were applied to explore the modification effect of PM on the temperature-childhood asthma hospitalization association. We found a greater effect of cold (5th percentile of temperature) on asthma during days with higher PM2.5 (RR 2.16, 95% CI 1.38, 3.38) or PM10 (RR 1.87, 95% CI1.20, 2.91) than that during days with lower PM2.5 (RR 1.64, 95% CI 1.06, 2.54) or PM10 (RR 1.52, 95% CI 0.98, 2.36). In addition, we observed a greater modification effect of PM2.5 on the cold-asthma association than did PM10, with a per 10 µg/m3 increase in PM2.5 and PM10 associated with increases of 0.065 and 0.025 for the RR corresponding to the 5th temperature percentile, respectively. For the temperature-related AF, moderate cold showed the largest change magnitude with the PM levels rising compared with other temperature ranges. For the subgroup, Females and those aged 6-18 years were more sensitive to the modification effect of PM2.5 or PM10 on the cold-asthma association. Our findings demonstrated that particulate matter could modify the associations between temperature and childhood asthma hospitalization.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Asma
/
Contaminantes Atmosféricos
/
Contaminación del Aire
Tipo de estudio:
Prognostic_studies
Límite:
Child
/
Female
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Environ Res
Año:
2022
Tipo del documento:
Article
País de afiliación:
China