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Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase.
Rabe, Patrick; Walla, Carla C; Goodyear, Noelle K; Welsh, Jordan; Southwart, Rebecca; Clifton, Ian; Linyard, James D S; Tumber, Anthony; Claridge, Tim D W; Myers, William K; Schofield, Christopher J.
Afiliación
  • Rabe P; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom. Electronic address: patrick.rabe@chem.ox.ac.uk.
  • Walla CC; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Goodyear NK; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Welsh J; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom; Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Southwart R; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Clifton I; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Linyard JDS; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Tumber A; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Claridge TDW; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
  • Myers WK; Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom. Electronic address: william.myers@chem.ox.ac.uk.
  • Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom. Electronic address: christopher.schofield@chem.ox.ac.uk.
J Biol Chem ; 298(9): 102249, 2022 09.
Article en En | MEDLINE | ID: mdl-35835215

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article