Terpenoids with anti-influenza activity from the leaves of Euphorbia leucocephala.
Nat Prod Res
; 37(6): 936-943, 2023 Mar.
Article
en En
| MEDLINE
| ID: mdl-35838448
ABSTRACT
Two rearranged terpenoids with a rare 3,4,5-trimethyl-cyclohexa-2,5-dien-1-one moiety, namely leucocephins A (1) and B (2), and a megastigmane, namely leucocephin C (3), as well as three known compounds, hollongdione (4), 3-acetoxy-lup-12,20(29)-diene (5), and ß-amyrin acetate (6) were isolated from the leaves of Euphorbia leucocephala. Their structures and absolute configurations were determined by spectroscopic methods and comparing with literature data. Compounds 4-6 exhibited potent anti-influenza A virus activity comparable to the positive control, betulinic acid.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Triterpenos
/
Euphorbia
Idioma:
En
Revista:
Nat Prod Res
Año:
2023
Tipo del documento:
Article
País de afiliación:
Taiwán