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Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer.
Hanna, Ann; Nixon, Mellissa J; Estrada, M Valeria; Sanchez, Violeta; Sheng, Quanhu; Opalenik, Susan R; Toren, Abigail L; Bauer, Joshua; Owens, Phillip; Mason, Frank M; Cook, Rebecca S; Sanders, Melinda E; Arteaga, Carlos L; Balko, Justin M.
Afiliación
  • Hanna A; Departments of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Nixon MJ; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Estrada MV; Department of Early Discovery Oncology, Merck & Co., Boston, MA, USA.
  • Sanchez V; Department of Pathology, Microbiology & Immunology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Sheng Q; Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Opalenik SR; Department of Pathology, Microbiology & Immunology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Toren AL; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Bauer J; Departments of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Owens P; Departments of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Mason FM; Vanderbilt Institute of Chemical Biology, Nashville, TN, USA.
  • Cook RS; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Sanders ME; Departments of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
  • Arteaga CL; Biomedical Engineering, Vanderbilt University School of Engineering, Nashville, TN, USA.
  • Balko JM; Department of Pathology, Microbiology & Immunology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2200 Pierce Ave, 777 PRB, Nashville, TN, 37232, USA.
Breast Cancer Res ; 24(1): 51, 2022 07 18.
Article en En | MEDLINE | ID: mdl-35850776
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas de Ciclo Celular / Fosfatasas de la Proteína Quinasa Activada por Mitógenos Límite: Animals Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas de Ciclo Celular / Fosfatasas de la Proteína Quinasa Activada por Mitógenos Límite: Animals Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos