Synergistic Effect of ß-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer.

Chang, Mario C; Mahar, Rohit; McLeod, Marc A; Giacalone, Anthony G; Huang, Xiumei; Boothman, David A; Merritt, Matthew E

Chang, Mario C; Mahar, Rohit; McLeod, Marc A; Giacalone, Anthony G; Huang, Xiumei; Boothman, David A; Merritt, Matthew E.

Afiliación

Chang MC; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Mahar R; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
McLeod MA; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Giacalone AG; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Huang X; Department of Radiation Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Boothman DA; Department of Radiation Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Merritt ME; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

Nutrients ; 14(15)2022 Jul 22.

Article en En | MEDLINE | ID: mdl-35893874

Asunto(s)

Ácido Aminooxiacético; Neoplasias de la Mama; Naftoquinonas; Ácido Aminooxiacético/uso terapéutico; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/metabolismo; Línea Celular Tumoral; Citratos; Femenino; Glutamatos/metabolismo; Humanos; NAD/metabolismo; NAD(P)H Deshidrogenasa (Quinona)/metabolismo; Naftoquinonas/farmacología; Naftoquinonas/uso terapéutico; Succinatos/metabolismo

Palabras clave

GC-MS; biogenic; cancer; isotopologue; metabolism; synergy

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Naftoquinonas / Ácido Aminooxiacético Límite: Female / Humans Idioma: En Revista: Nutrients Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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