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A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.
Kirkland, David; Whitwell, James; Smith, Robert; Hashimoto, Kiyohiro; Ji, Zhiying; Kenny, Julia; Koyama, Naoki; Lovell, David P; Martus, Hans-Jörg; Meurer, Krista; Roberts, Daniel; Takeiri, Akira; Uno, Yoshifumi; van der Leede, Bas-Jan; White, Paul; Zeller, Andreas.
Afiliación
  • Kirkland D; Kirkland Consulting, PO Box 79, Tadcaster LS24 0AS, UK. Electronic address: dkirkland@genetoxconsulting.co.uk.
  • Whitwell J; Labcorp Drug Development, Otley Road, Harrogate HG3 1PY, UK.
  • Smith R; Labcorp Drug Development, Otley Road, Harrogate HG3 1PY, UK.
  • Hashimoto K; Takeda Pharmaceutical Company Limited, Research, Drug Safety Research and Evaluation, Fujisawa, Japan.
  • Ji Z; Bristol Myers Squibb Company, Nonclinical Safety, 1 Squibb Drive, New Brunswick, NJ 08903, USA.
  • Kenny J; GlaxoSmithKline, Park Road, Ware SG12 0DP, UK.
  • Koyama N; Eisai Co., Ltd, Global Drug Safety, Tsukuba-shi, Ibaraki, Japan.
  • Lovell DP; Public Health Research Institute (PHRI), St George's Hospital Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK.
  • Martus HJ; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
  • Meurer K; BASF SE, Li444, Speyererstrasse 2, 67117 Limburgerhof, Germany.
  • Roberts D; Charles River Laboratories, Skokie, IL, USA.
  • Takeiri A; Chugai Pharmaceutical Co., Ltd., Translational Research Div., 1-135 Komakado, Gotemba, Shizuoka, Japan.
  • Uno Y; LSI Medience Co., 1-13-4, Tokyo 101-8517, Japan.
  • van der Leede BJ; Non-Clinical Safety, Janssen Research & Development, a Division of Janssen Pharmaceutica N.V., Turnhoutseweg 30, 2340 Beerse, Belgium.
  • White P; Environmental Health Science and Research Bureau, Health Canada, Ottawa, Ontario, Canada.
  • Zeller A; F. Hoffmann-La Roche Ltd., Pharmaceutical Sciences, pRED Innovation Center Basel, 4070 Basel, Switzerland.
Mutat Res Genet Toxicol Environ Mutagen ; 879-880: 503503, 2022.
Article en En | MEDLINE | ID: mdl-35914859
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aneugénicos / Mutágenos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Mutat Res Genet Toxicol Environ Mutagen Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aneugénicos / Mutágenos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Mutat Res Genet Toxicol Environ Mutagen Año: 2022 Tipo del documento: Article