Ionizing radiation damage and repair from 3D-genomic perspective.

Zheng, Yang; Li, Hao; Bo, Xiaochen; Chen, Hebing

Zheng, Yang; Li, Hao; Bo, Xiaochen; Chen, Hebing.

Afiliación

Zheng Y; Institute of Health Service and Transfusion Medicine, Beijing 100850, China; State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China.
Li H; Institute of Health Service and Transfusion Medicine, Beijing 100850, China.
Bo X; Institute of Health Service and Transfusion Medicine, Beijing 100850, China. Electronic address: boxc@bmi.ac.cn.
Chen H; Institute of Health Service and Transfusion Medicine, Beijing 100850, China. Electronic address: chenhb@bmi.ac.cn.

Trends Genet ; 39(1): 1-4, 2023 01.

Article en En | MEDLINE | ID: mdl-35934594

ABSTRACT

ABSTRACT

Ionizing radiation (IR)-induced DNA damage and repair are complex and occur at hierarchical chromatin structures; radiobiology needs to be studied from a 3D-genomic perspective. Differences in IR damage and repair throughout the 3D genome may help to explain differences in radiosensitivity.

Asunto(s)

Daño del ADN; Reparación del ADN; Reparación del ADN/genética; Daño del ADN/genética; Radiación Ionizante; Tolerancia a Radiación/genética; Genómica

Palabras clave

3D genome; ionizing radiation; radiosensitivity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Daño del ADN / Reparación del ADN Idioma: En Revista: Trends Genet Asunto de la revista: GENETICA Año: 2023 Tipo del documento: Article País de afiliación: China

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