Considerations in the Development of Physically Stable High Drug Load API- Polymer Amorphous Solid Dispersions in the Glassy State.

Newman, Ann; Zografi, George

Newman, Ann; Zografi, George.

Afiliación

Newman A; Seventh Street Development Group, PO Box 251, Kure Beach NC 28449, United States. Electronic address: ann.newman@SeventhStreetDev.com.
Zografi G; School of Pharmacy, University of Wisconsin-Madison, United States.

J Pharm Sci ; 112(1): 8-18, 2023 01.

Article en En | MEDLINE | ID: mdl-35948156

Asunto(s)

Polímeros; Polímeros/química; Estabilidad de Medicamentos; Cristalización; Peso Molecular; Solubilidad

Palabras clave

Crystallization; Glass; High concentration; Mobility; Physical stability; Polymer concentration; Stabilization; amorphous solid dispersion (ASD)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polímeros Idioma: En Revista: J Pharm Sci Año: 2023 Tipo del documento: Article

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