Lymphostatin, a virulence factor of attaching and effacing <i>Escherichia coli</i>, inhibits proliferation and cytokine responses of human T cells in a manner associated with cell cycle arrest but not apoptosis or necrosis.

Ruamsap, Nattaya; Riyapa, Donporn; Janesomboon, Sujintana; Stevens, Joanne M; Pichyangkul, Sathit; Pattanapanyasat, Kovit; Demons, Samandra T; Stevens, Mark P; Korbsrisate, Sunee

Lymphostatin, a virulence factor of attaching and effacing Escherichia coli, inhibits proliferation and cytokine responses of human T cells in a manner associated with cell cycle arrest but not apoptosis or necrosis.

Ruamsap, Nattaya; Riyapa, Donporn; Janesomboon, Sujintana; Stevens, Joanne M; Pichyangkul, Sathit; Pattanapanyasat, Kovit; Demons, Samandra T; Stevens, Mark P; Korbsrisate, Sunee.

Afiliación

Ruamsap N; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Riyapa D; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Janesomboon S; Center for Research and Innovation, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, Thailand.
Stevens JM; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Pichyangkul S; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, United Kingdom.
Pattanapanyasat K; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Demons ST; Department for Research and Development, Siriraj Center of Research Excellence for Microparticle and Exosome in Diseases, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Stevens MP; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Korbsrisate S; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, United Kingdom.

Front Cell Infect Microbiol ; 12: 941939, 2022.

Article en En | MEDLINE | ID: mdl-35967844

Asunto(s)

Toxinas Bacterianas; Infecciones por Escherichia coli; Proteínas de Escherichia coli; Escherichia coli; Linfocitos T; Apoptosis; Toxinas Bacterianas/inmunología; Linfocitos T CD8-positivos/inmunología; Puntos de Control del Ciclo Celular/inmunología; División Celular; Proliferación Celular/fisiología; Citocinas/biosíntesis; Citocinas/inmunología; Escherichia coli Enteropatógena/inmunología; Escherichia coli Enteropatógena/patogenicidad; Escherichia coli/inmunología; Escherichia coli/patogenicidad; Infecciones por Escherichia coli/inmunología; Proteínas de Escherichia coli/inmunología; Humanos; Interleucina-2; Interleucina-4; Leucocitos Mononucleares/inmunología; Necrosis; Linfocitos T/inmunología; Factores de Virulencia/inmunología

Palabras clave

G0/G1 cell cycle arrest; apoptosis and necrosis; cyclin expression; cytokine suppression; enteropathogenic Escherichia coli; inhibit T cell proliferation; lymphostatin

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Linfocitos T / Proteínas de Escherichia coli / Escherichia coli / Infecciones por Escherichia coli Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Front Cell Infect Microbiol Año: 2022 Tipo del documento: Article País de afiliación: Tailandia

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google