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Regenerative medicine meets translational oncology: Modeling leukemic bone marrow niche.
Borbaran-Bravo, Natalia; Arreba-Tutusaus, Patricia; Ritter, Malte U; Nasri, Masoud; Klimiankou, Maksim; Skokowa, Julia.
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  • Borbaran-Bravo N; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany.
  • Arreba-Tutusaus P; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany.
  • Ritter MU; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany.
  • Nasri M; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany.
  • Klimiankou M; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany.
  • Skokowa J; Division of Translational Oncology, Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany. Electronic address: julia.skokowa@med.uni-tuebingen.de.
Cell Rep Med ; 3(8): 100724, 2022 08 16.
Article en En | MEDLINE | ID: mdl-35977470
ABSTRACT
Most studies on leukemia focus on leukemia cells as isolated objects without considering the bone marrow niche. Pal et al. have recreated the bone marrow niche using induced pluripotent stem cells (iPSCs), identifying CDH2 as a therapeutically druggable leukemia-promoting factor.1.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Médula Ósea / Leucemia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Med Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Médula Ósea / Leucemia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Med Año: 2022 Tipo del documento: Article País de afiliación: Alemania