RNA-seq transcriptome profiling of liver regeneration in mice identifies the miR-34b-5p/phosphoinositide-dependent protein kinase 1 axis as a potential target for hepatocyte proliferation.

Lei, Xiaohua; Dai, Xiaoming; Wang, Qian; Long, Ruchang; Xiang, Zhiqiang; Li, Huajian; Long, Zhangtao; Zhang, Chao; Zhu, Zhu

Lei, Xiaohua; Dai, Xiaoming; Wang, Qian; Long, Ruchang; Xiang, Zhiqiang; Li, Huajian; Long, Zhangtao; Zhang, Chao; Zhu, Zhu.

Afiliación

Lei X; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Dai X; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Wang Q; The First Affiliated Hospital, Department of Reproductive Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Long R; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Xiang Z; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Li H; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Long Z; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Zhang C; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Zhu Z; The First Affiliated Hospital, Department of Hepatobiliary Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, China; The First Affiliated Hospital, Department of Education and Training, Hengyang Medical School, University of South China, Hengyang, Hunan, China. Electronic

Biochem Biophys Res Commun ; 627: 111-121, 2022 10 30.

Article en En | MEDLINE | ID: mdl-36030652

Asunto(s)

MicroARNs; ARN Largo no Codificante; 1-Fosfatidilinositol 4-Quinasa/genética; Regiones no Traducidas 3'; Animales; Proliferación Celular/genética; Perfilación de la Expresión Génica; Hepatocitos/metabolismo; Hiperplasia; Regeneración Hepática/genética; Ratones; MicroARNs/metabolismo; Fosfatidilinositoles; Proteínas Quinasas/genética; ARN Largo no Codificante/genética; ARN Mensajero/genética; RNA-Seq

Palabras clave

Competition endogenous RNA; Gene regulation; Hepatocyte proliferation; Liver regeneration; Phosphoinositide-dependent protein kinase 1; miR-34b-5p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: MicroARNs / ARN Largo no Codificante Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2022 Tipo del documento: Article País de afiliación: China

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