How we approach coagulopathy with vascular anomalies.
Pediatr Blood Cancer
; 69 Suppl 3: e29353, 2022 08.
Article
en En
| MEDLINE
| ID: mdl-36070211
ABSTRACT
Some vascular anomalies can present with challenging hematologic aberrations. Kaposiform hemangioendothelioma (KHE) may be complicated with Kasabach-Merritt phenomenon (KMP) and stagnant blood flow in slow-flow malformations can promote activation and consumption of coagulation factors, which results in bleeding and clotting known as localized intravascular coagulopathy (LIC). These patients can experience significant morbidity secondary to pain due to thrombosis and are at higher risk of hematologic complications during surgical procedures. No standard of care has been established to prevent or manage these complications. This review focuses on the management of coagulopathy in children and adults with vascular anomalies.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sarcoma de Kaposi
/
Trastornos de la Coagulación Sanguínea
/
Malformaciones Vasculares
/
Síndrome de Kasabach-Merritt
/
Hemangioendotelioma
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Child
/
Humans
Idioma:
En
Revista:
Pediatr Blood Cancer
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos