Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord.

Huang, Yulin; Hao, Jing; Yang, Xuli; Xu, Li; Liu, Yue; Sun, Yu'e; Gu, Xiaoping; Zhang, Wei; Ma, Zhengliang

Huang, Yulin; Hao, Jing; Yang, Xuli; Xu, Li; Liu, Yue; Sun, Yu'e; Gu, Xiaoping; Zhang, Wei; Ma, Zhengliang.

Afiliación

Huang Y; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China.
Hao J; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China.
Yang X; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China.
Xu L; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China.
Liu Y; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Sun Y; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Gu X; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Zhang W; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China. zhangwei2008@njmu.edu.cn.
Ma Z; Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, China. mazhengliang1964@nju.edu.cn.

Neurochem Res ; 48(1): 305-314, 2023 Jan.

Article en En | MEDLINE | ID: mdl-36104611

Asunto(s)

Hiperalgesia; Inflamasomas; Ratas; Ratones; Animales; Hiperalgesia/metabolismo; Inflamasomas/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Microglía/metabolismo; Privación de Sueño/complicaciones; Privación de Sueño/tratamiento farmacológico; Privación de Sueño/metabolismo; Ratas Sprague-Dawley; Médula Espinal/metabolismo; Dolor Postoperatorio/metabolismo

Palabras clave

Chronic postsurgical pain; Microglia activation; NLRP3; Reactive oxygen species; Sleep deprivation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inflamasomas / Hiperalgesia Límite: Animals Idioma: En Revista: Neurochem Res Año: 2023 Tipo del documento: Article País de afiliación: China

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