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Prediction of drug-induced liver injury and cardiotoxicity using chemical structure and in vitro assay data.
Ye, Lin; Ngan, Deborah K; Xu, Tuan; Liu, Zhichao; Zhao, Jinghua; Sakamuru, Srilatha; Zhang, Li; Zhao, Tongan; Xia, Menghang; Simeonov, Anton; Huang, Ruili.
Afiliación
  • Ye L; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Ngan DK; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Xu T; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Liu Z; National Center for Toxicological Research, U.S. Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
  • Zhao J; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Sakamuru S; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Zhang L; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Zhao T; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Xia M; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Simeonov A; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.
  • Huang R; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA. Electronic address: huangru@mail.nih.gov.
Toxicol Appl Pharmacol ; 454: 116250, 2022 11 01.
Article en En | MEDLINE | ID: mdl-36150479
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos