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Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity.
Kaplan, Anat Levit; Confair, Danielle N; Kim, Kuglae; Barros-Álvarez, Ximena; Rodriguiz, Ramona M; Yang, Ying; Kweon, Oh Sang; Che, Tao; McCorvy, John D; Kamber, David N; Phelan, James P; Martins, Luan Carvalho; Pogorelov, Vladimir M; DiBerto, Jeffrey F; Slocum, Samuel T; Huang, Xi-Ping; Kumar, Jain Manish; Robertson, Michael J; Panova, Ouliana; Seven, Alpay B; Wetsel, Autumn Q; Wetsel, William C; Irwin, John J; Skiniotis, Georgios; Shoichet, Brian K; Roth, Bryan L; Ellman, Jonathan A.
Afiliación
  • Kaplan AL; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Confair DN; Department of Chemistry, Yale University, New Haven, CT, USA.
  • Kim K; Department of Pharmacology, University of North Carolina, Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Barros-Álvarez X; Department of Pharmacy, Yonsei University, Incheon, Republic of Korea.
  • Rodriguiz RM; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Yang Y; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
  • Kweon OS; Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, USA.
  • Che T; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • McCorvy JD; Department of Chemistry, Yale University, New Haven, CT, USA.
  • Kamber DN; Center for Clinical Pharmacology, Department of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA.
  • Phelan JP; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Martins LC; Department of Chemistry, Yale University, New Haven, CT, USA.
  • Pogorelov VM; Department of Chemistry, Yale University, New Haven, CT, USA.
  • DiBerto JF; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Slocum ST; Biochemistry Department, Institute for Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Huang XP; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
  • Kumar JM; Department of Pharmacology, University of North Carolina, Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Robertson MJ; Department of Pharmacology, University of North Carolina, Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Panova O; National Institute of Mental Health Psychoactive Drug Screening Program, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Seven AB; Department of Pharmacology, University of North Carolina, Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Wetsel AQ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Wetsel WC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Irwin JJ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Skiniotis G; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
  • Shoichet BK; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. william.wetsel@duke.edu.
  • Roth BL; Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, USA. william.wetsel@duke.edu.
  • Ellman JA; Department of Cell Biology, Duke University Medical Center, Durham, NC, USA. william.wetsel@duke.edu.
Nature ; 610(7932): 582-591, 2022 10.
Article en En | MEDLINE | ID: mdl-36171289
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Receptor de Serotonina 5-HT2A / Antidepresivos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Receptor de Serotonina 5-HT2A / Antidepresivos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos