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Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study.
Reel, Parminder S; Reel, Smarti; van Kralingen, Josie C; Langton, Katharina; Lang, Katharina; Erlic, Zoran; Larsen, Casper K; Amar, Laurence; Pamporaki, Christina; Mulatero, Paolo; Blanchard, Anne; Kabat, Marek; Robertson, Stacy; MacKenzie, Scott M; Taylor, Angela E; Peitzsch, Mirko; Ceccato, Filippo; Scaroni, Carla; Reincke, Martin; Kroiss, Matthias; Dennedy, Michael C; Pecori, Alessio; Monticone, Silvia; Deinum, Jaap; Rossi, Gian Paolo; Lenzini, Livia; McClure, John D; Nind, Thomas; Riddell, Alexandra; Stell, Anthony; Cole, Christian; Sudano, Isabella; Prehn, Cornelia; Adamski, Jerzy; Gimenez-Roqueplo, Anne-Paule; Assié, Guillaume; Arlt, Wiebke; Beuschlein, Felix; Eisenhofer, Graeme; Davies, Eleanor; Zennaro, Maria-Christina; Jefferson, Emily.
Afiliación
  • Reel PS; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee DD2 4BF, UK. Electronic address: p.s.reel@dundee.ac.uk.
  • Reel S; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee DD2 4BF, UK.
  • van Kralingen JC; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • Langton K; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Lang K; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK; Department of Endocrinology, Queen Elizabeth Hospital Birmingham, University
  • Erlic Z; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, UniversitätsSpital Zürich (USZ) und Universität Zürich (UZH), Zurich, Switzerland.
  • Larsen CK; Université Paris Cité, PARCC, INSERM, F-75006 Paris, France.
  • Amar L; Université Paris Cité, PARCC, INSERM, F-75006 Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Unité Hypertension artérielle, Paris, France.
  • Pamporaki C; Department of Medicine III, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Mulatero P; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Italy.
  • Blanchard A; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Centre d'Investigations Cliniques 9201 Paris, France.
  • Kabat M; Department of Hypertension, National Institute of Cardiology, Warsaw, Poland.
  • Robertson S; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • MacKenzie SM; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • Taylor AE; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Peitzsch M; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Ceccato F; UOC Endocrinologia, Dipartimento di Medicina DIMED, Azienda Ospedaliera-Università di Padova, Padua, Italy.
  • Scaroni C; UOC Endocrinologia, Dipartimento di Medicina DIMED, Azienda Ospedaliera-Università di Padova, Padua, Italy.
  • Reincke M; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany.
  • Kroiss M; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany; Clinical Chemistry and Laboratory Medicine, Core Unit Clinical Mass Spectrometry, Universitätsklinikum Würzburg, Germany; Schwerpunkt Endokrinologie/Diabetologie, Medizinische Klinik und Poliklinik
  • Dennedy MC; The Discipline of Pharmacology and Therapeutics, School of Medicine, National University of Ireland 33 Galway, Ireland.
  • Pecori A; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Italy.
  • Monticone S; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Italy.
  • Deinum J; Department of Medicine, Section of Vascular Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Rossi GP; Internal & Emergency Medicine- ESH Specialized Hypertension Center, Department of Medicine-DIMED, University of Padua, Padua, Italy.
  • Lenzini L; Internal & Emergency Medicine- ESH Specialized Hypertension Center, Department of Medicine-DIMED, University of Padua, Padua, Italy.
  • McClure JD; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • Nind T; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee DD2 4BF, UK.
  • Riddell A; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • Stell A; Department of Computing and Information Systems, University of Melbourne, Melbourne, Australia.
  • Cole C; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee DD2 4BF, UK.
  • Sudano I; University Hospital Zurich University Heart Center, Cardiology, and University of Zurich, Zurich, Switzerland.
  • Prehn C; Metabolomics and Proteomics Core (MPC), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Adamski J; Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Sing
  • Gimenez-Roqueplo AP; Université Paris Cité, PARCC, INSERM, F-75006 Paris, France; Service de Génétique, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015 Paris, France.
  • Assié G; Université de Paris, Institut Cochin, INSERM, CNRS, F-75014 Paris, France; Department of Endocrinology, Center for Rare Adrenal Diseases, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France.
  • Arlt W; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK; Department of Endocrinology, Queen Elizabeth Hospital Birmingham, University
  • Beuschlein F; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, UniversitätsSpital Zürich (USZ) und Universität Zürich (UZH), Zurich, Switzerland; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany.
  • Eisenhofer G; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany; Department of Medicine III, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Davies E; School of Cardiovascular and Metabolic Health, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK.
  • Zennaro MC; Université Paris Cité, PARCC, INSERM, F-75006 Paris, France; Service de Génétique, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015 Paris, France. Electronic address: maria-christina.zennaro@inserm.fr.
  • Jefferson E; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee DD2 4BF, UK; Institute of Health & Wellbeing, University of Glasgow, Glasgow G12 8RZ, UK. Electronic address: e.r.jefferson@dundee.ac.uk.
EBioMedicine ; 84: 104276, 2022 Oct.
Article en En | MEDLINE | ID: mdl-36179553
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: MicroARNs / Hipertensión Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: MicroARNs / Hipertensión Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article