Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma via the JAK/STAT and NF-&#954;B Signaling Pathways.

Guo, Huiwen; Zheng, Lixiang; Guo, Yepin; Han, Lu; Yu, Jing; Lai, Fuchong

Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma via the JAK/STAT and NF-κB Signaling Pathways.

Guo, Huiwen; Zheng, Lixiang; Guo, Yepin; Han, Lu; Yu, Jing; Lai, Fuchong.

Afiliación

Guo H; College of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine.
Zheng L; College of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine.
Guo Y; College of Humanities, Jiangxi University of Chinese Medicine.
Han L; College of Humanities, Jiangxi University of Chinese Medicine.
Yu J; College of Humanities, Jiangxi University of Chinese Medicine.
Lai F; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province.

Biol Pharm Bull ; 45(10): 1466-1475, 2022.

Article en En | MEDLINE | ID: mdl-36184504

Asunto(s)

Neoplasias Óseas; Osteosarcoma; Animales; Apoptosis; Benzoatos; Neoplasias Óseas/tratamiento farmacológico; Cadherinas; Caspasa 3/metabolismo; Línea Celular Tumoral; Proliferación Celular; Glucósidos; Humanos; Quinasas Janus/metabolismo; Quinasas Janus/farmacología; Quinasas Janus/uso terapéutico; Ratones; Ratones Desnudos; FN-kappa B/metabolismo; Osteosarcoma/tratamiento farmacológico; Transducción de Señal; Proteína X Asociada a bcl-2

Palabras clave

Janus kinase 2 (JAK2); curculigoside; nuclear factor-κB (NF-κB); osteosarcoma; signal transducer and activator of transcription 3 (STAT3)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biol Pharm Bull Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2022 Tipo del documento: Article

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