The international consensus classification of myeloid neoplasms and acute Leukemias: myeloproliferative neoplasms.
Am J Hematol
; 98(1): 166-179, 2023 01.
Article
en En
| MEDLINE
| ID: mdl-36200127
ABSTRACT
A group of international experts, including hematopathologists, oncologists, and geneticists were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World Health Organization classification system for hematopoietic tumors. After careful deliberation, the group introduced the new International Consensus Classification (ICC) for Myeloid Neoplasms and Acute Leukemias. This current in-depth review focuses on the ICC-2022 category of JAK2 mutation-prevalent myeloproliferative neoplasms (MPNs) essential thrombocythemia, polycythemia vera, primary myelofibrosis, and MPN, unclassifiable. The ICC MPN subcommittee chose to preserve the primary role of bone marrow morphology in disease classification and diagnostics, while also acknowledging the complementary role of genetic markers for establishing clonality, facilitating MPN subtype designation, and disease prognostication.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Policitemia Vera
/
Leucemia
/
Trastornos Mieloproliferativos
Límite:
Humans
Idioma:
En
Revista:
Am J Hematol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Alemania