The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF-&#945;.

Song, Daisheng; Peng, Kai; Palmer, Bradleigh E; Lee, Frank S

The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF-α.

Song, Daisheng; Peng, Kai; Palmer, Bradleigh E; Lee, Frank S.

Afiliación

Song D; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Peng K; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Palmer BE; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lee FS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

EMBO J ; 41(22): e112059, 2022 11 17.

Article en En | MEDLINE | ID: mdl-36219563

Asunto(s)

Policitemia; Humanos; Ratones; Animales; Policitemia/genética; Policitemia/metabolismo; Prolina Dioxigenasas del Factor Inducible por Hipoxia/genética; Prolina Dioxigenasas del Factor Inducible por Hipoxia/metabolismo; Procolágeno-Prolina Dioxigenasa/química; Dedos de Zinc; Hipoxia; Subunidad alfa del Factor 1 Inducible por Hipoxia/genética; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo

Palabras clave

NACA; Tibetan adaptation; hypoxia-inducible factor; prolyl hydroxylase domain protein 2

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Policitemia Límite: Animals / Humans Idioma: En Revista: EMBO J Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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