Ultrahigh resolution MS<sup>1</sup>/MS<sup>2</sup>-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action.

Fan, Teresa W-M; Sun, Qiushi; Higashi, Richard M

Ultrahigh resolution MS¹/MS²-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action.

Fan, Teresa W-M; Sun, Qiushi; Higashi, Richard M.

Afiliación

Fan TW; Center for Environmental and Systems Biochemistry (CESB), University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA. Electronic address: teresa.fan@uky.edu.
Sun Q; Center for Environmental and Systems Biochemistry (CESB), University of Kentucky, Lexington, Kentucky, USA.
Higashi RM; Center for Environmental and Systems Biochemistry (CESB), University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.

J Biol Chem ; 298(12): 102586, 2022 12.

Article en En | MEDLINE | ID: mdl-36223837

Asunto(s)

Arsenitos; Ácido Selenioso; Arsenitos/farmacología; Isótopos de Carbono/química; Marcaje Isotópico/métodos; Redes y Vías Metabólicas; Metabolómica/métodos; Espectrometría de Masas en Tándem; Humanos

Palabras clave

[(13)C(5),(15)N(2)]-glutamine; [(13)C(6)]-glucose; arsenite; metabolic pathway reconstruction; positional isotopologues; selenite; stable isotope resolved metabolomics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arsenitos / Ácido Selenioso Límite: Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article

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