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Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.
El Hamdaoui, Yamina; Zheng, Fang; Fritz, Nikolas; Ye, Lian; Tran, Mai Anh; Schwickert, Kevin; Schirmeister, Tanja; Braeuning, Albert; Lichtenstein, Dajana; Hellmich, Ute A; Weikert, Dorothee; Heinrich, Markus; Treccani, Giulia; Schäfer, Michael K E; Nowak, Gabriel; Nürnberg, Bernd; Alzheimer, Christian; Müller, Christian P; Friedland, Kristina.
Afiliación
  • El Hamdaoui Y; Pharmacology & Toxicology, Institute for Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg Universität Mainz (JGU), Mainz, Germany.
  • Zheng F; Institute of Physiology and Pathophysiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Fritz N; Pharmacology & Toxicology, Institute for Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg Universität Mainz (JGU), Mainz, Germany.
  • Ye L; Pharmacology & Toxicology, Institute for Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg Universität Mainz (JGU), Mainz, Germany.
  • Tran MA; Institute of Organic Chemistry and Macromolecular Chemistry, Faculty of Chemistry and Earth Science, Friedrich Schiller University Jena, Jena, Germany.
  • Schwickert K; Biochemistry, Department of Chemistry, Johannes-Gutenberg Universität Mainz, Mainz, Germany.
  • Schirmeister T; Pharmacology & Toxicology, Institute for Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg Universität Mainz (JGU), Mainz, Germany.
  • Braeuning A; Pharmacology & Toxicology, Institute for Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg Universität Mainz (JGU), Mainz, Germany.
  • Lichtenstein D; Department of Food Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany.
  • Hellmich UA; Department of Food Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany.
  • Weikert D; Institute of Organic Chemistry and Macromolecular Chemistry, Faculty of Chemistry and Earth Science, Friedrich Schiller University Jena, Jena, Germany.
  • Heinrich M; Biochemistry, Department of Chemistry, Johannes-Gutenberg Universität Mainz, Mainz, Germany.
  • Treccani G; Cluster of Excellence "Balance of the Microverse", Friedrich-Schiller-Uniersität Jena, Jena, Germany.
  • Schäfer MKE; Center for Biomolecular Magnetic Resonance, Goethe-University, Frankfurt, Germany.
  • Nowak G; Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Nürnberg B; Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Alzheimer C; Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Müller CP; Institute of Anatomy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Friedland K; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1 (Bld. 505), 55131, Mainz, Germany.
Mol Psychiatry ; 27(12): 5070-5085, 2022 12.
Article en En | MEDLINE | ID: mdl-36224261
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Floroglucinol / Terpenos / Hypericum / Canal Catiónico TRPC6 / Antidepresivos Límite: Animals Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Floroglucinol / Terpenos / Hypericum / Canal Catiónico TRPC6 / Antidepresivos Límite: Animals Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania