D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function.

Dangelmaier, Carol; Mauri, Benjamin; Patel, Akruti; Kunapuli, Satya P; Kostyak, John C

Dangelmaier, Carol; Mauri, Benjamin; Patel, Akruti; Kunapuli, Satya P; Kostyak, John C.

Afiliación

Dangelmaier C; Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Mauri B; Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Patel A; Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Kunapuli SP; Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Kostyak JC; Cardeza Center for Hemostasis, Thrombosis, and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Int J Mol Sci ; 23(19)2022 Sep 29.

Article en En | MEDLINE | ID: mdl-36232816

Asunto(s)

Plaquetas/metabolismo; Receptores Purinérgicos P2Y12/metabolismo; Adenosina Difosfato/metabolismo; Animales; Ácido Aspártico/metabolismo; Hemorragia/genética; Hemorragia/metabolismo; Humanos; Ratones; Agregación Plaquetaria; Pruebas de Función Plaquetaria; Antagonistas del Receptor Purinérgico P2Y/farmacología; Receptores Purinérgicos P2Y12/química; Receptores Purinérgicos P2Y12/genética

Palabras clave

adenosine diphosphate; blood platelets; hemostasis; platelet aggregation; thrombosis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plaquetas / Receptores Purinérgicos P2Y12 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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