Costs of management of acute respiratory infections in older adults: A systematic review and meta-analysis.
J Glob Health
; 12: 04096, 2022 11 08.
Article
en En
| MEDLINE
| ID: mdl-36342670
ABSTRACT
Background:
Acute respiratory infections (ARIs) accounted for an estimated 3.9 million deaths worldwide in 2015, of which 56% occurred in adults aged 60 years or older. We aimed to identify the cost of ARI management in older adults (≥50 years) in order to develop an evidence base to assist decision-making for resource allocation and inform clinical practice.Methods:
We searched 8 electronic databases including Global Health, Medline and EMBASE for studies published between January 1, 2000 and December 31, 2021. Total management costs per patient per ARI episode were extracted and meta-analysis was conducted by World Health Organization (WHO) region and World Bank income level. All costs were converted and inflated to Euros () (2021 average exchange rate). The quality of included studies and the potential risk of bias were evaluated.Results:
A total of 42 publications were identified for inclusion, reporting cost data for 8 082 752 ARI episodes in older adults across 20 countries from 2001 to 2021. The majority (86%) of studies involved high-income countries based in Europe, North America and Western Pacific. The mean cost per episode was 17 803.9 for inpatient management and 128.9 for outpatient management. Compared with costs reported for patients aged <65 years, inpatient costs were 154.1, 7 018.8 and 8 295.6 higher for patients aged 65-74 years, 75-84 years and over 85 years. ARI management of at-risk patients with comorbid conditions and patients requiring higher level of care, incurred substantially higher costs for hospitalization 735.9 and 1317.3 respectively.Conclusions:
ARIs impose a substantial economic burden on health systems, governments, patients and societies. This study identified high ARI management costs in older adults, reinforcing calls for investment by global health players to quantify and address the scale of the challenge. There are large gaps in data availability from low-income countries, especially from South East Asia and Africa regions.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones del Sistema Respiratorio
Tipo de estudio:
Health_economic_evaluation
/
Prognostic_studies
/
Systematic_reviews
Límite:
Aged
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Glob Health
Año:
2022
Tipo del documento:
Article
País de afiliación:
Reino Unido