The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer's disease.

Folorunso, Oluwarotimi O; Harvey, Theresa L; Brown, Stephanie E; Chelini, Gabriele; Berretta, Sabina; Balu, Darrick T

Folorunso, Oluwarotimi O; Harvey, Theresa L; Brown, Stephanie E; Chelini, Gabriele; Berretta, Sabina; Balu, Darrick T.

Afiliación

Folorunso OO; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Translational Psychiatry Laboratory, McLean Hospital, Belmont, MA, USA.
Harvey TL; Translational Psychiatry Laboratory, McLean Hospital, Belmont, MA, USA.
Brown SE; Translational Psychiatry Laboratory, McLean Hospital, Belmont, MA, USA.
Chelini G; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Translational Neuroscience Laboratory, Mclean Hospital, Belmont, MA, USA.
Berretta S; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Translational Neuroscience Laboratory, Mclean Hospital, Belmont, MA, USA.
Balu DT; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Translational Psychiatry Laboratory, McLean Hospital, Belmont, MA, USA. Electronic address: dbalu@mclean.harvard.edu.

Neurosci Lett ; 792: 136958, 2023 01 01.

Article en En | MEDLINE | ID: mdl-36356820

Asunto(s)

Enfermedad de Alzheimer; Humanos; Ratones; Animales; Astrocitos; Amígdala del Cerebelo; Placa Amiloide; Modelos Animales de Enfermedad; Serina

Palabras clave

5xFAD; Complement C3; D-serine; Extrasynaptic N-methyl-D-aspartate receptors; Glial fibrillary acidic protein

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Revista: Neurosci Lett Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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