Epigenetic regulation by metabolites from the gut microbiome.
Benef Microbes
; 13(6): 437-443, 2022 Dec 07.
Article
en En
| MEDLINE
| ID: mdl-36377583
The gut microbiome can metabolise food components, such as dietary fibres and various phytochemicals; and the microbiome can also synthesise some nutrients, for example B vitamins. The metabolites produced by bacteria and other micro-organisms in the colon can have implications for health and disease risk. Some of these metabolites are epigenetically active, and can contribute to changes in the chemical modification and structure of chromatin by affecting the activity and expression of epigenetically-active enzymes, for example histone deacetylases and DNA methyltransferases. The epigenetic activity of such gut microbiome metabolites is reviewed herein.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Probióticos
/
Epigénesis Genética
Idioma:
En
Revista:
Benef Microbes
Año:
2022
Tipo del documento:
Article