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Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
Ishii, Kenta; Yokoyama, Yukihiro; Yonekawa, Yoshihiko; Hayashi, Daisuke; Kinoshita, Fumie; Kuwatsuka, Yachiyo; Okuno, Masataka; Natsume, Seiji; Minami, Takayuki; Sugawara, Gen; Seita, Kazuaki; Sato, Fumiya; Aoba, Taro; Shimizu, Yasuhiro; Kurumiya, Yasuhiro; Maeda, Atsuyuki; Yamaguchi, Ryuzo; Hiramatsu, Kazuhiro; Ebata, Tomoki.
Afiliación
  • Ishii K; Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Yokoyama Y; Department of General Surgery, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan.
  • Yonekawa Y; Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Hayashi D; Division of Perioperative Medicine, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Kinoshita F; Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Kuwatsuka Y; Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Okuno M; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Natsume S; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Minami T; Department of Gastroenterological Surgery, Aichi Cancer Centre Hospital, Nagoya, Aichi, Japan.
  • Sugawara G; Department of Gastroenterological Surgery, Aichi Cancer Centre Hospital, Nagoya, Aichi, Japan.
  • Seita K; Department of Surgery, Toyota Kosei Hospital, Toyota, Aichi, Japan.
  • Sato F; Department of Surgery, Toyota Kosei Hospital, Toyota, Aichi, Japan.
  • Aoba T; Department of Surgery, Ogaki Municipal Hospital, Ogaki, Gifu, Japan.
  • Shimizu Y; Department of Surgery, Kasugai Municipal Hospital, Kasugai, Aichi, Japan.
  • Kurumiya Y; Department of General Surgery, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan.
  • Maeda A; Department of Gastroenterological Surgery, Aichi Cancer Centre Hospital, Nagoya, Aichi, Japan.
  • Yamaguchi R; Department of Surgery, Toyota Kosei Hospital, Toyota, Aichi, Japan.
  • Hiramatsu K; Department of Surgery, Ogaki Municipal Hospital, Ogaki, Gifu, Japan.
  • Ebata T; Department of Surgery, Kasugai Municipal Hospital, Kasugai, Aichi, Japan.
Br J Surg ; 110(2): 159-165, 2023 01 10.
Article en En | MEDLINE | ID: mdl-36379883
Removing part of the pancreas is an operation with a risk of major blood loss. Tranexamic acid is a drug thought to reduce blood loss. This study asked the question, 'Does tranexamic acid reduce blood loss during surgery on the pancreas?' Half of patients received tranexamic acid during surgery. The other half received only standard care. This study showed that tranexamic acid did not decrease the blood loss during the surgery and may have little effect in patients having a pancreaticoduodenectomy.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Tranexámico / Antifibrinolíticos Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: Br J Surg Año: 2023 Tipo del documento: Article País de afiliación: Japón
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Tranexámico / Antifibrinolíticos Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: Br J Surg Año: 2023 Tipo del documento: Article País de afiliación: Japón