Rosmarinic Acid Prevents Cisplatin-Induced Liver and Kidney Injury by Inhibiting Inflammatory Responses and Enhancing Total Antioxidant Capacity, Thereby Activating the Nrf2 Signaling Pathway.

Xiang, Yifei; Ji, Min; Wu, Liqin; Lv, Li; Liang, Qiuling; Deng, Ruihan; Deng, Zhaoyou; Liu, Xia; Ren, Lingyi; Feng, Xin; He, Jiakang

Xiang, Yifei; Ji, Min; Wu, Liqin; Lv, Li; Liang, Qiuling; Deng, Ruihan; Deng, Zhaoyou; Liu, Xia; Ren, Lingyi; Feng, Xin; He, Jiakang.

Afiliación

Xiang Y; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Ji M; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Wu L; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Lv L; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Liang Q; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Deng R; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Deng Z; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Liu X; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Ren L; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.
Feng X; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA.
He J; College of Animal Science and Technology, Guangxi University, Nanning 530005, China.

Molecules ; 27(22)2022 Nov 13.

Article en En | MEDLINE | ID: mdl-36431915

Asunto(s)

Antioxidantes; Factor 2 Relacionado con NF-E2; Ratones; Animales; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; Antioxidantes/metabolismo; Cisplatino/farmacología; Factor de Necrosis Tumoral alfa/metabolismo; Interleucina-6/metabolismo; FN-kappa B/metabolismo; Riñón; Transducción de Señal; Hígado; Antiinflamatorios/farmacología; ARN Mensajero/metabolismo; Ácido Rosmarínico

Palabras clave

Nrf2; acute liver and kidney injury; cisplatin; inflammation; oxidative stress; rosmarinic acid

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor 2 Relacionado con NF-E2 / Antioxidantes Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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